About

By understanding a virus’ evolutionary trajectory in advance, we can build prospective vaccines.

What if we could engineer prospective vaccines to elicit ideal immune responses against present and emerging health threats, a priori?

By the time we design, manufacture and approve vaccines, many viruses have already evolved, making it hard to keep pace and fight back.

Our pioneering approach to vaccinology centers on a unique platform, Octavia™, that combines biological insights with advanced AI/ML to harness the power of prediction. Our Octavia platform predicts viral evolution, delivers improved vaccines, and assesses how well they will perform before entering clinical trials.

Apriori was founded in 2020 by Flagship Pioneering.

Advisors

Jesse Bloom, PhD

Scientific Advisor

Professor, Fred Hutch

HHMI Investigator

Ara Darzi, OM, KBE, PC, FRS

Special Advisor and Chairman, Preemptive Health & Medicine Initiative, Flagship Pioneering

Tom DiLenge

Senior Partner, Flagship Pioneering

Global Public Policy, Regulatory & Governmental Strategy

Stephen Hahn, MD

CEO-Partner, Flagship Pioneering and CEO, Harbinger Health

U.S. FDA Commissioner 2019-21

Ian Hudson, MD

Consultant

Former CEO, Medicines and Healthcare Products Regulatory Agency

Former Senior Advisor, The Gates Foundation

Kathrin Jansen, PhD

Former SVP and Head of Vaccines R&D, Pfizer

Wellington Sun, MD

Former Head of Vaccine Strategy, Moderna

Former Director, FDA Division of Vaccines

Andrew Weber

Senior Advisor

Former Assistant U.S. Secretary of Defense